Reaction discovery with pincer complexes
Oleg V. Ozerov
Texas A&M University
The
name “pincer” has become reserved for tridentate chelating ligands that
bind to a metal center in a meridional (T-shaped) fashion. They are
typically denoted by the three donor atoms attached to the metal. Our
group has devoted considerable attention to the chemistry of the
T-shaped three-coordinate pincer-ligated fragments of group 9 metals
(Co, Rh, or Ir). These are highly unsaturated species that cannot be
isolated in their free form, but can be generated in solution. They
display remarkable propensity for insertion into various X-Y bonds in
oxidative addition reactions. The presentation will describe the various
oxidative addition reactions of aryl halides and pseudohalides, and
show how the study of these reactions can lead to discovery of new
catalytic transformations. The emphasis will be on how molecular design,
elementary reaction discovery, and development of effective new
catalysts are intricately but not always obviously related.
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